Figuring out how much CBD oil to take can feel like trying to navigate through a complicated maze. The sheer volume of CBD brands on the market can create confusion for consumers, and when you take a closer look, it’s not difficult to understand why. Not only do vendors use different source materials (CBD-rich cannabis vs. industrial hemp, different strains, etc.), but they also implement different extraction techniques .
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The amount of CBD needed to produce significant effects varies by condition, according to both Blessing and Carson. “In clinical trials for schizophrenia they would give 800 milligrams,” says Blessing. “In our clinical trial to treat PTSD, we are giving 600 mg per day.” In the clinical trial for Epidiolex, Carson says, the clinicians administered 10 milligrams per kilogram the subject weighed — meaning a person who weighs 50 kilograms (or 110 pounds) would be given 500 milligrams of CBD.
When discussing coffee, some coffee roasts do however include both CBD and THC, and these can potentially deliver a pretty significant high. However, what people really seem to be interested in as of late is pure CBD coffee, which you can drink every single morning just like a regular cup of joe — it provides loads of health benefits (see below), without getting you stoned in any way.
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Two additional studies in this area were done using CBD oil. In the first one, 214 participants would take 0.9 to 2.3 grams of oil per 1 pound of body weight. CBD successfully reduced seizures by a median of 36.5%. The second study focused on children who suffered from Dravet syndrome. Dravet syndrome is a type of epilepsy that happens in early infancy. Normally high temperatures and fevers trigger it. The results of the second study showed that CBD oil reduced seizures significantly.
Still, there are many reasons why patients may prefer to avoid all THC. For example, THC-free products offer an option for active military that want to incorporate CBD for pain or post-traumatic stress disorder (PTSD), but are prohibited from consuming products containing THC. First responders – such as firefighters, police officers, and EMTs – can now benefit from the balancing properties of CBD without fear of violating their employers’ restrictions. Competing athletes, many of who face restrictive testing policies from their sports’ governing bodies, can incorporate CBD into their regimen without fear of negative consequences. Parents of children who rely on the balancing properties of CBD to reduce seizure activity or manage symptoms of autism often prefer to avoid exposing their kids to even trace amounts of THC that exist in other hemp oil products.
In most cases (and in all cases in which the coffee shop doesn’t want to risk being sued), coffee shops can’t advertise CBD as doing much of anything, one way or another. While clinical trials attempt to determine an effective dose for a particular condition, says Esther, the growing “wellness empire” is free to leave the effects to your imagination. “People who are selling CBD don’t even have to make specific claims. The relationship between the actual amount of CBD and the effect doesn’t have to be very specific, because there is no specific effect that they’re talking about,” says Blessing. “So if I have a CBD latte, I might feel a little relaxed, or a little less neurotic, or who knows.”
Selective breeding of cannabis plants has expanded and diversified as commercial and therapeutic markets develop. Some growers in the U.S. succeeded in lowering the proportion of CBD-to-THC to accommodate customers who preferred varietals that were more mind-altering due to the higher THC and lower CBD content. Hemp is classified as any part of the cannabis plant containing no more than 0.3% THC in dry weight form (not liquid or extracted form).
The isolation of CBD was recorded back on 1940 by two independent investigation groups. The group of Adams and colleges successfully isolated it from marihuana 1. At the same time Jacob and Todd successfully isolated the cannabidiol from indian hemp resin 2. But was not until 1963 that Mechoulam and Shyo discovered the chemical structure of the CBD and enlightening the comprehension of the nature of the cannabinoids 3. At the next year 1964 Gaoni and Mechoulam finally elucidated the chemical structure of the main psychoactive compound of cannabis the THC matching the starting point of the modern pharmacology of cannabis 4.
In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. For a more comprehensive look at these and other studies, visit our medical research and education page.